Combination antioxidant therapy prevents epileptogenesis and modifies chronic epilepsy
نویسندگان
چکیده
منابع مشابه
Seizures, Epileptogenesis, and Epilepsy
ber of diverse variables. Some of these factors, such as genes that influence seizure susceptibility, are internal. Others, which alter normal brain excitability, such as traumatic brain injury, are external. As described elsewhere in this volume, these variables can AQ? Specific cross-ref to chapter number? have different and distinct effects. For example, genes may influence both the developm...
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Progress in epilepsy treatment in last decades of the twentieth century included a number of new antiepileptic drugs that were expected to reduce the number of patients with drug-resistant epilepsy. However, it soon became obvious that, in spite of the improving safety of antiepileptic treatment, the efficacy of new agents was not much better than the old drugs. The number of patients with drug...
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Background: Gap junctions (GJs) provide direct intercellular communications that are formed by hexameric protein subunits, called connexin (Cx). The role of Cxs in epileptogenesis has not received sufficient attention. Hippocampus with critical function in epileptogenesis has a wide network of GJs. We examined the protein expression levels of hippocampal Cx36 (the prominent Cx present between G...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2019
ISSN: 2213-2317
DOI: 10.1016/j.redox.2019.101278